Western blot analysis of extracts of various cell lines using CNOT8 Polyclonal Antibody at 1:1000 dilution.
CNOT8 Polyclonal Antibody
E-AB-62996
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCNOT8 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionHas 3-5 poly(A exoribonuclease activity for synthetic poly(A RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
- UNSPSC12352203