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Coilin antibody

GTX112570
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetCOIL
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Overview

  • Supplier
    GeneTex
  • Product Name
    Coilin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.66 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8161
  • Target name
    COIL
  • Target description
    coilin
  • Target synonyms
    CLN80; coilin; coilin p80; p80; p80-coilin
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP38432
  • Protein Name
    Coilin
  • Scientific Description
    The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Revealing RCOR2 as a regulatory component of nuclear speckles. Rivera C et al., 2021 Nov 24, Epigenetics Chromatin
    Read more
  • Systematic Identification and Functional Validation of New snoRNAs in Human Muscle Progenitors. Bogard B et al., 2021 Sep 13, Noncoding RNA
    Read more
  • The structurally conserved TELR region on shelterin protein TPP1 is essential for telomerase processivity but not recruitment. Sandhu R et al., 2021 Jul 27, Proc Natl Acad Sci U S A
    Read more