Coilin antibody

Name: Coilin antibody
SKU: GTX112570_G10
Availability: BackOrder

GTX112570

ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetCOIL

Overview

Supplier
GeneTex
Product Name
Coilin antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.66 mg/ml
Conjugate
Unconjugated
Gene ID8161
Target name
COIL
Target description
coilin
Target synonyms
CLN80, p80-coilin, coilin, coilin p80, p80
Host
Rabbit
Isotype
IgG
Protein IDP38432
Protein Name
Coilin
Scientific Description
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Rivera C, Verbel-Vergara D, Arancibia D, et al. Revealing RCOR2 as a regulatory component of nuclear speckles. Epigenetics Chromatin. 2021,14(1):51. doi: 10.1186/s13072-021-00425-4
Read this paper
Bogard B, Francastel C, Hubé F. Systematic Identification and Functional Validation of New snoRNAs in Human Muscle Progenitors. Noncoding RNA. 2021,7(3). doi: 10.3390/ncrna7030056
Read this paper
Sandhu R, Sharma M, Wei D, et al. The structurally conserved TELR region on shelterin protein TPP1 is essential for telomerase processivity but not recruitment. Proc Natl Acad Sci U S A. 2021,118(30). doi: 10.1073/pnas.2024889118
Read this paper