
WB analysis of mouse lung tissue lysate (35ug/lane) using GTX80984 COL18A1 antibody, N-term.
COL18A1 antibody, N-term
GTX80984
Overview
- SupplierGeneTex
- Product NameCOL18A1 antibody, N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. FACS: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- FormulationLiquid
- Gene ID80781
- Target nameCOL18A1
- Target descriptioncollagen type XVIII alpha 1 chain
- Target synonymsantiangiogenic agent; collagen alpha-1(XVIII) chain; collagen, type XVIII, alpha 1; endostatin; GLCC; KNO; KNO1; KS; multi-functional protein MFP
- Protein IDP39060
- Protein NameCollagen alpha-1(XVIII) chain
- Scientific DescriptionThis gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203