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WB analysis of mouse lung tissue lysate (35ug/lane) using GTX80984 COL18A1 antibody, N-term.
WB analysis of mouse lung tissue lysate (35ug/lane) using GTX80984 COL18A1 antibody, N-term.
WB analysis of mouse lung tissue lysate (35ug/lane) using GTX80984 COL18A1 antibody, N-term.

COL18A1 antibody, N-term

GTX80984
GeneTex
TargetCOL18A1
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    COL18A1 antibody, N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000. FACS: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Formulation
    Liquid
  • Gene ID80781
  • Target name
    COL18A1
  • Target description
    collagen type XVIII alpha 1 chain
  • Target synonyms
    antiangiogenic agent; collagen alpha-1(XVIII) chain; collagen, type XVIII, alpha 1; endostatin; GLCC; KNO; KNO1; KS; multi-functional protein MFP
  • Protein IDP39060
  • Protein Name
    Collagen alpha-1(XVIII) chain
  • Scientific Description
    This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203