Bio-Connect

Combretastatin A-1 phosphate tetrasodium

ORB1984509
Biorbyt
CAS Number288847-34-7
Product group Chemicals
Estimated Purity98.00%
Molecular Weight580.24
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    Combretastatin A-1 phosphate tetrasodium
  • Delivery Days Customer
    10
  • CAS Number
    288847-34-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.00%
  • Molecular Formula
    C18H18Na4O12P2
  • Molecular Weight
    580.24
  • Scientific Description
    Combretastatin A-1 phosphate (OXi-4503) tetrasodium, a prodrug of Combretastatin A-1, is a tubulin-binding microtubule polymerization inhibitor targeting the colchicine-binding site. By inducing tubulin depolymerization, it inhibits the Wnt/beta-catenin pathway and deactivates AKT, possessing both anti-tumor and anti-vascular properties.
  • SMILES
    [Na].COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)c(OP(O)(O)=O)c1OP(O)(O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200