Complement Factor D antibody [4M47]

GeneTex

Complement Factor D antibody [4M47]

9

WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Monoclonal

4M47

500 ug/ml

Unconjugated

CFD

complement factor D

ADIPSIN; ADN; C3 convertase activator; complement factor D; complement factor D preproprotein; D component of complement (adipsin); DF; PFD; properdin factor D

Mouse

IgG2

Complement factor D

This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015]

Human

-20°C or -80°C,2°C to 8°C

12352203