Conoidin A [18080-67-6]

MedChem Express

Conoidin A [18080-67-6]

10

18080-67-6

Research Use Only

99.32

C10H8Br2N2O2

347.99

Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. Conoidin A covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 microM. Conoidin A also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII)[1][2]. Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease[3].

[O-][N+]1=C(C(CBr)=[N+](C2=C1C=CC=C2)[O-])CBr

-20°C,2°C to 8°C

12352200