Conoidin A [18080-67-6]

TargetMol Chemicals

Conoidin A

4

18080-67-6

Chemical

Research Use Only

Conoidin A

98%

C10H8Br2N2O2

347.99

Conoidin A is a cell-permeable inhibitor of the T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. It covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 microM. It also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII). Conoidin A has antioxidant, neuroprotective effects and can be used for research on ischaemic heart disease.

3 years

[O-][n+]1c(CBr)c(CBr)[n+]([O-])c2ccccc12

-20°C

12352200