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Copanlisib dihydrochloride [1402152-13-9]

Copanlisib dihydrochloride [1402152-13-9]

T14998
TargetMol Chemicals
CAS Number1402152-13-9
Product group Chemicals
Estimated Purity99.05%
Molecular Weight553.44
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Copanlisib dihydrochloride
  • Delivery Days Customer
    4
  • CAS Number
    1402152-13-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Copanlisib dihydrochloride
  • Estimated Purity
    99.05%
  • Molecular Formula
    C23H30Cl2N8O4
  • Molecular Weight
    553.44
  • Scientific Description
    Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is an ATP-competitive pan-class I PI3K inhibitor, with IC50 values of 0.5 nM for PI3Kalpha, 0.7 nM for PI3Kdelta, 3.7 nM for PI3Kbeta, and 6.4 nM for PI3Kgamma. It exhibits superior antitumor activity and demonstrates more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.Cl.COc1c(OCCCN2CCOCC2)ccc2C3=NCCN3C(NC(=O)c3cnc(N)nc3)=Nc12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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