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COPD antibody [GT1318]

GTX630562
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetARCN1
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Overview

  • Supplier
    GeneTex
  • Product Name
    COPD antibody [GT1318]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GT1318
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID372
  • Target name
    ARCN1
  • Target description
    archain 1 coat protein complex I subunit delta
  • Target synonyms
    COPD, SRMMD, SSMG, coatomer subunit delta, COPI coat complex subunit delta, archain vesicle transport protein 1, coatomer delta subunit, coatomer protein complex, subunit delta, coatomer protein delta-COP, delta-COP, delta-coat protein
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP48444
  • Protein Name
    Coatomer subunit delta
  • Scientific Description
    This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or trafficking. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Steiner A, Hrovat-Schaale K, Prigione I, et al. Deficiency in coatomer complex I causes aberrant activation of STING signalling. Nat Commun. 2022,13(1):2321. doi: 10.1038/s41467-022-29946-6
    Read this paper
  • Mukai K, Ogawa E, Uematsu R, et al. Homeostatic regulation of STING by retrograde membrane traffic to the ER. Nat Commun. 2021,12(1):61. doi: 10.1038/s41467-020-20234-9
    Read this paper