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Cot inhibitor-2 [915363-56-3]

Cot inhibitor-2 [915363-56-3]

T10866
TargetMol Chemicals
CAS Number915363-56-3
Product group Chemicals
Estimated Purity98.87%
Molecular Weight539.43
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Cot inhibitor-2 [915363-56-3]
  • Delivery Days Customer
    4
  • CAS Number
    915363-56-3
  • Certification
    Research Use Only
  • Chemical Name
    Cot inhibitor-2
  • Estimated Purity
    98.87%
  • Molecular Formula
    C26H25Cl2FN8
  • Molecular Weight
    539.43
  • Scientific Description
    Cot inhibitor-2 is a cot (Tpl2/MAP3K8) inhibitor (IC50: 1.6 nM) with potency, selectivity and oral activity. cot inhibitor-2 inhibits LPS-stimulated TNF-alpha production in human whole blood with an IC50 of 0.3 microM.
  • Shelf life instruction
    3 years
  • SMILES
    CCN1CCC(CC1)n1cc(CNc2cc(Cl)c3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)nn1
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000