CPI-455 HCl [2095432-28-1]

TargetMol Chemicals

CPI-455 HCl

72

2095432-28-1

Chemical

Research Use Only

CPI-455 HCl

C16H15ClN4O

314.77

CPI-455 is a specific KDM5 inhibitor with IC50 value of 10 +/- 1 nM for full-length KDM5A in enzymatic assays, elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer cell line models treated with targeted agents or standard chemotherapy.

3 years

Cl.CC(C)c1c([nH]c2c(cnn2c1=O)C#N)-c1ccccc1

-20°C

12352200