CPI-455 (hydrochloride)
HY-100421A
CAS Number2095432-28-1
Product group Chemicals
Molecular Weight314.77
Overview
- SupplierMedChem Express
- Product NameCPI-455 (hydrochloride) [2095432-28-1]
- Delivery Days Customer10
- CAS Number2095432-28-1
- Molecular FormulaC16H15ClN4O
- Molecular Weight314.77
- Scientific DescriptionCPI-455 hydrochloride is a specific, pan- KDM5 inhibitor with an IC 50 of 10 nM for KDM5A. CPI-455 hydrochloride mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents [1] .
- SMILESN#CC1=C2NC(C3=CC=CC=C3)=C(C(C)C)C(N2N=C1)=O.[H]Cl
- UNSPSC12352200