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CPI-455 (hydrochloride)

HY-100421A
MedChem Express
CAS Number2095432-28-1
Product group Chemicals
Molecular Weight314.77
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CPI-455 (hydrochloride) [2095432-28-1]
  • Delivery Days Customer
    10
  • CAS Number
    2095432-28-1
  • Certification
    Research Use Only
  • Molecular Formula
    C16H15ClN4O
  • Molecular Weight
    314.77
  • Scientific Description
    CPI-455 hydrochloride is a specific, pan- KDM5 inhibitor with an IC 50 of 10 nM for KDM5A. CPI-455 hydrochloride mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents [1] .
  • SMILES
    N#CC1=C2NC(C3=CC=CC=C3)=C(C(C)C)C(N2N=C1)=O.[H]Cl
  • UNSPSC
    12352200