CPT1A antibody [C1C2], Internal
GTX114337
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetCPT1A
Overview
- SupplierGeneTex
- Product NameCPT1A antibody [C1C2], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID1374
- Target nameCPT1A
- Target descriptioncarnitine palmitoyltransferase 1A
- Target synonymscarnitine O-palmitoyltransferase 1, liver isoform; carnitine palmitoyltransferase 1A (liver); carnitine palmitoyltransferase I, liver; CPT I; CPT1; CPT1-L; CPTI-L; L-CPT1
- HostRabbit
- IsotypeIgG
- Protein IDP50416
- Protein NameCarnitine O-palmitoyltransferase 1, liver isoform
- Scientific DescriptionThe mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Quantitative Profiling of Oxylipin Reveals the Mechanism of Pien-Tze-Huang on Alcoholic Liver Disease. Zhu Z et al., 2021, Evid Based Complement Alternat MedRead more
- Downregulation of fatty acid oxidation by involvement of HIF-1alpha and PPARgamma in human gastric adenocarcinoma and related clinical significance. Ezzeddini R et al., 2021 May, J Physiol BiochemRead more
- Ugonin J improves metabolic disorder and ameliorates nonalcoholic fatty liver disease by regulating the AMPK/AKT signaling pathway. Chang TC et al., 2021 Jan, Pharmacol ResRead more
- Antrodia cinnamomea Confers Obesity Resistance and Restores Intestinal Barrier Integrity in Leptin-deficient Obese Mice. Tsai YT et al., 2020 Mar 10, NutrientsRead more
- Helminthostachys zeylanica alleviates hepatic steatosis and insulin resistance in diet-induced obese mice. Chang TC et al., 2019 Dec 13, BMC Complement Altern MedRead more
- Fenofibrate induces human hepatoma Hep3B cells apoptosis and necroptosis through inhibition of thioesterase domain of fatty acid synthase. You BJ et al., 2019 Mar 1, Sci RepRead more
- Orlistat Displays Antitumor Activity and Enhances the Efficacy of Paclitaxel in Human Hepatoma Hep3B Cells. You BJ et al., 2019 Feb 18, Chem Res ToxicolRead more
- The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2. Tarling EJ et al., 2015 Apr, Arterioscler Thromb Vasc BiolRead more
- Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer. Roy D et al., 2014, Cancer MetabRead more
- Metabolomics reveals that carnitine palmitoyltransferase-1 is a novel target for oxidative inactivation in human cells. Setoyama D et al., 2013 Dec, Genes CellsRead more