Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using CPT1B(GTX117231) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with GTX11304 (Red) at 1:2000.
Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using CPT1B(GTX117231) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with GTX11304 (Red) at 1:2000.
CPT1B antibody [C1C2], Internal
GTX117231
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCPT1B
Overview
- SupplierGeneTex
- Product NameCPT1B antibody [C1C2], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.8 mg/ml
- ConjugateUnconjugated
- Gene ID1375
- Target nameCPT1B
- Target descriptioncarnitine palmitoyltransferase 1B
- Target synonymsCPT1-M, CPT1M, CPTI, CPTI-M, M-CPT1, MCCPT1, MCPT1, carnitine O-palmitoyltransferase 1, muscle isoform, carnitine O-palmitoyltransferase 1B, carnitine palmitoyltransferase 1B (muscle), carnitine palmitoyltransferase I-like protein
- HostRabbit
- IsotypeIgG
- Protein IDQ92523
- Protein NameCarnitine O-palmitoyltransferase 1, muscle isoform
- Scientific DescriptionThe protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and one of the transcripts is bicistronic. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chen W, Xu Z, You W, et al. Cold exposure alters lipid metabolism of skeletal muscle through HIF-1α-induced mitophagy. BMC Biol. 2023,21(1):27. doi: 10.1186/s12915-023-01514-4Read this paper
- Dang Y, Xu J, Zhu M, et al. Gan-Jiang-Ling-Zhu decoction alleviates hepatic steatosis in rats by the miR-138-5p/CPT1B axis. Biomed Pharmacother. 2020,127:110127. doi: 10.1016/j.biopha.2020.110127Read this paper
- Wen SY, Velmurugan BK, Day CH, et al. High density lipoprotein (HDL) reverses palmitic acid induced energy metabolism imbalance by switching CD36 and GLUT4 signaling pathways in cardiomyocyte. J Cell Physiol. 2017,232(11):3020-3029. doi: 10.1002/jcp.26007Read this paper
- Zhang Y, Fang X, Dai M, et al. Cardiac-specific down-regulation of carnitine palmitoyltransferase-1b (CPT-1b) prevents cardiac remodeling in obese mice. Obesity (Silver Spring). 2016,24(12):2533-2543. doi: 10.1002/oby.21665Read this paper
Datasheet
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