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Crizotinib (PF-02341066) [877399-52-5]

S1068
Selleck Chemicals
Product group Chemicals
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Crizotinib (PF-02341066) [877399-52-5]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Crizotinib (PF-02341066) is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM in cell-based assays, respectively. It is also a potent ROS1 inhibitor with Ki value less than 0.025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines.
  • UNSPSC
    12352200

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