WB analysis of LNCAP, A431, MCF7 and HT1080 lysates using CRK antibody at a dilution of 1:1,000.
WB analysis of LNCAP, A431, MCF7 and HT1080 lysates using CRK antibody at a dilution of 1:1,000.
CRK antibody [3H7-E5-H8]
GTX49212
Overview
- SupplierGeneTex
- Product NameCRK antibody [3H7-E5-H8]
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3H7-E5-H8
- ConjugateUnconjugated
- Gene ID1398
- Target nameCRK
- Target descriptionCRK proto-oncogene, adaptor protein
- Target synonymsadapter molecule crk; CRKII; p38; proto-oncogene c-Crk; v-crk avian sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene-like protein
- HostMouse
- IsotypeIgG2b
- Protein IDP46108
- Protein NameAdapter molecule crk
- Scientific DescriptionThis gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203