Western blot analysis of extracts of various cell lines using CRK/CRKII Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using CRK/CRKII Polyclonal Antibody at 1:1000 dilution.
CRK Polyclonal Antibody
E-AB-62054
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCRK Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
- UNSPSC12352203