IHC-P analysis of human glioma tissue using GTX19352 CRMP5 antibody [CR-3]. Left : Primary antibody Right : Negative control without primary antibody Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes Dilution : 1:50
![WB analysis of tissue whole cell extracts (30 μg lysate) of Mouse Brain (Lane 1), Rat Brain (lane 2), SH-SY5Y (lane 3), NTERA 2 (Lane 4), and PC 12 (lane 5) using GTX19352 CRMP5 antibody [CR-3]. Dilution : 1:1000](https://www.genetex.com/upload/website/prouct_img/normal/GTX19352/GTX19352_1570_WB_w_23060620_377.webp "WB analysis of tissue whole cell extracts (30 μg lysate) of Mouse Brain (Lane 1), Rat Brain (lane 2), SH-SY5Y (lane 3), NTERA 2 (Lane 4), and PC 12 (lane 5) using GTX19352 CRMP5 antibody [CR-3]. Dilution : 1:1000")
![ICC/IF analysis of SH-SY5Y cells using GTX19352 CRMP5 antibody [CR-3]. Panel e is a no primary antibody control. Green : Primary antibody Blue : Nuclei Red : Actin Fixation : 4% paraformaldehyde Permeabilization : 0.1% Triton X-100 for 10 minute Dilution : 1:250 dilution in 0.1% BSA and incubated for 3 hours at room temperature](https://www.genetex.com/upload/website/prouct_img/normal/GTX19352/GTX19352_368_ICC-IF_w_23060620_618.webp "ICC/IF analysis of SH-SY5Y cells using GTX19352 CRMP5 antibody [CR-3]. Panel e is a no primary antibody control. Green : Primary antibody Blue : Nuclei Red : Actin Fixation : 4% paraformaldehyde Permeabilization : 0.1% Triton X-100 for 10 minute Dilution : 1:250 dilution in 0.1% BSA and incubated for 3 hours at room temperature")
![IHC-P analysis of human tonsil tissue using GTX19352 CRMP5 antibody [CR-3]. Left : Primary antibody Right : Negative control without primary antibody Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX19352/GTX19352_1071_IHC-P_w_23060620_306.webp "IHC-P analysis of human tonsil tissue using GTX19352 CRMP5 antibody [CR-3]. Left : Primary antibody Right : Negative control without primary antibody Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes Dilution : 1:50")
IHC-P analysis of human glioma tissue using GTX19352 CRMP5 antibody [CR-3]. Left : Primary antibody Right : Negative control without primary antibody Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes Dilution : 1:50
CRMP5 antibody [CR-3]
GTX19352
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse, Rat
TargetDPYSL5
Overview
- SupplierGeneTex
- Product NameCRMP5 antibody [CR-3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:50 - 1:1,000. ICC/IF: 1:250. IHC-Fr: 1:50 - 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCR-3
- ConjugateUnconjugated
- Gene ID56896
- Target nameDPYSL5
- Target descriptiondihydropyrimidinase like 5
- Target synonymsCRAM, CRMP-5, CRMP5, CV2, RTSC4, Ulip6, dihydropyrimidinase-related protein 5, CRMP3-associated molecule, DRP-5, ULIP-6, UNC33-like phosphoprotein 6, collapsin response mediator protein-5
- HostRat
- IsotypeIgG2a
- Protein IDQ9BPU6
- Protein NameDihydropyrimidinase-related protein 5
- Scientific DescriptionThis gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
- ReactivityBovine, Human, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC41116161
References
- Elevated Hippocampal CRMP5 Mediates Chronic Stress-Induced Cognitive Deficits by Disrupting Synaptic Plasticity, Hindering AMPAR Trafficking, and Triggering Cytokine Release.Read this paper
- Collapsin response mediator protein 5 (CRMP5) causes social deficits and accelerates memory loss in an animal model of Alzheimers disease. Lin YS et al., 2019 Oct, NeuropharmacologyRead this paper
Datasheet
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