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CRT0044876 [6960-45-8]

CRT0044876 [6960-45-8]

T6456
TargetMol Chemicals
CAS Number6960-45-8
Product group Chemicals
Estimated Purity98.27%
Molecular Weight206.15
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    CRT0044876 [6960-45-8]
  • Delivery Days Customer
    4
  • CAS Number
    6960-45-8
  • Certification
    Research Use Only
  • Chemical Name
    CRT0044876
  • Estimated Purity
    98.27%
  • Molecular Formula
    C9H6N2O4
  • Molecular Weight
    206.15
  • Scientific Description
    CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 microM.
  • Shelf life instruction
    3 years
  • SMILES
    OC(=O)c1cc2cccc([N+]([O-])=O)c2[nH]1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Long K, Gu L, Li L, et al. Small-molecule inhibition of APE1 induces apoptosis, pyroptosis, and necroptosis in non-small cell lung cancer. Cell Death Dis. 2021,12(6):503. doi: 10.1038/s41419-021-03804-7
    Read this paper