Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA706631LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA706631LA01HU at dilution of 1:100
CRTC2 Antibody
CSB-PA706631LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCRTC2
Overview
- SupplierCusabio
- Product NameCRTC2 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID200186
- Target nameCRTC2
- Target descriptionCREB regulated transcription coactivator 2
- Target synonymsCREB-regulated transcription coactivator 2; TORC2; TORC-2; transducer of regulated cAMP response element-binding protein (CREB) 2
- HostRabbit
- IsotypeIgG
- Protein IDQ53ET0
- Protein NameCREB-regulated transcription coactivator 2
- Scientific DescriptionTranscriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 \Ser-133\ phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203