IHC image of CSB-PA747623LA01HU diluted at 1:500 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
CRTC3 Antibody
CSB-PA747623LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCRTC3
Overview
- SupplierCusabio
- Product NameCRTC3 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID64784
- Target nameCRTC3
- Target descriptionCREB regulated transcription coactivator 3
- Target synonymsCREB-regulated transcription coactivator 3; TORC3; TORC-3; transducer of regulated cAMP response element-binding protein (CREB) 3; transducer of regulated CREB protein 3
- HostRabbit
- IsotypeIgG
- Protein IDQ6UUV7
- Protein NameCREB-regulated transcription coactivator 3
- Scientific DescriptionTranscriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 \Ser-133\ phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203