CSN5i-3 [2375740-98-8]

MedChem Express

CSN5i-3 [2375740-98-8]

9

2375740-98-8

Research Use Only

99.95

C28H29F2N5O2

505.56

CSN5i-3 is a potent, selective and orally available inhibitor of CSN5/Jab1, and inhibits CSN-catalysed Cul1 deneddylation with an IC50 value of 5.8 nM[1].

O=C(C1=CC(C(F)F)=NN1C(C)C)NC2=CC(C3=CC=CC=C3)=C([C@@H]4N5C(CCC[C@@H]4O)=CN=C5)C=C2

-20°C

12352200