More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/CSN5i-3 [2375740-98-8]
CSN5i-3 [2375740-98-8]

CSN5i-3 [2375740-98-8]

T10895
TargetMol Chemicals
CAS Number2375740-98-8
DownloadMSDS
Product group Chemicals
Estimated Purity99.80%
Molecular Weight505.56
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    CSN5i-3 [2375740-98-8]
  • Delivery Days Customer
    9
  • CAS Number
    2375740-98-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    CSN5i-3
  • Estimated Purity
    99.80%
  • Molecular Formula
    C28H29F2N5O2
  • Molecular Weight
    505.56
  • Scientific Description
    CSN5i-3 is a potent, selective, and orally available inhibitor of the proteolytic subunit of the CSN complex, CSN5. It inhibits CSN-catalyzed Cul1 deneddylation with an IC50 value of 5.8 nM. CSN5i-3 has a killing effect on a variety of cancer cells and can be used as an anticancer drug. [2]
  • Shelf life instruction
    3 years
  • SMILES
    CC(C)n1nc(cc1C(=O)Nc1ccc([C@H]2[C@@H](O)CCCc3cncn23)c(c1)-c1ccccc1)C(F)F
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Targeted inhibition of the COP9 signalosome for treatment of cancer. Schlierf A et al., 2016 Oct 24, Nat Commun
    Read more

Related products

Product group Chemicals
MedChem Express
CSN5i-3HY-112134
CAS Number2375740-98-8
Estimated Purity99.95
Molecular Weight505.56
  • SizePrice
Product group Chemicals
AbMole BioScience
CSN5i-3M14676
CAS Number2375740-98-8
Molecular Weight505.56
  • SizePrice
Product group Chemicals
Biorbyt
CSN5i-3ORB1709975
CAS Number2375740-98-8
Estimated Purity98%
Molecular Weight505.56
  • SizePrice