CtIP antibody [19E8]

GeneTex

CtIP antibody [19E8]

9

WB: 1:500-1:1000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, Other Application

Research Use Only

Monoclonal

1 mg/ml

Unconjugated

RBBP8

RB binding protein 8, endonuclease

COM1, CTIP, JAWAD, JWDS, RIM, SAE2, SCKL2, DNA endonuclease RBBP8, CTBP-interacting protein, retinoblastoma binding protein 8, sporulation in the absence of SPO11 protein 2 homolog

Mouse

IgG1

DNA endonuclease RBBP8

The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]

Human, Mouse

-20°C or -80°C,2°C to 8°C

41116161