CTLA-4, Human (HEK293, His)
HY-P70684
Protein IDP16410
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameCTLA-4, Human (HEK293, His)
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity98.0
- Gene ID1493
- Target nameCTLA4
- Target descriptioncytotoxic T-lymphocyte associated protein 4
- Target synonymsALPS5; CD; CD152; celiac disease 3; CELIAC3; CTLA-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; cytotoxic T-lymphocyte protein 4; cytotoxic T-lymphocyte-associated serine esterase-4; GRD4; GSE; IDDM12; insulin-dependent diabetes mellitus 12; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
- Protein IDP16410
- Protein NameCytotoxic T-lymphocyte protein 4
- Scientific DescriptionThe CTLA-4 protein is a key inhibitory receptor and a major negative regulator of T cell responses in coordination of immune regulation. Its unique property is its significantly increased affinity for B7 ligands (CD80/CD86) compared with CD28. CTLA-4 Protein, Human (HEK293, His) is the recombinant human-derived CTLA-4 protein, expressed by HEK293 , with C-6*His labeled tag.
- Storage Instruction-20°C
- UNSPSC41116100



![CD152 [CTLA-4] (human) (rec.) (His) (Prod. No. AG-40B-0228) binds to the receptor CD80 (human): Fc (mouse) (rec.) (Prod. No. CHI-HF-211CD80). Method: CD80 (human): Fc (mouse) (rec.) (Prod. No. CHI-HF-211CD80) is coated on an ELISA plate at 1 microg/ml overnight at 4°C. CD152 [CTLA-4] (human) (rec.) (His) (Prod. No. AG-40B-0228) (red line) or a control protein (His) (green line) is incubated (starting at a concentration of 8,000 ng/ml with a two-fold serial dilution) during one hour at RT and the interaction is then detected using an anti-His-(HRP).](https://adipogen.com/pub/media/catalog/product/a/g/ag-40b-0228-binding_assay-400px.jpg)