CTPI-2 [68003-38-3]

MedChem Express

CTPI-2 [68003-38-3]

10

68003-38-3

Research Use Only

99.95

C13H9ClN2O6S

356.74

CTPI-2 is a third-generation mitochondrial citrate carrier SLC25A1 inhibitor with a KD of 3.5 microM. CTPI-2 inhibits glycolysis, PPARgamma, and its downstream target the glucose transporter GLUT4. CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet. Antitumor activity[1][2].

O=C(O)C1=CC=CC=C1NS(=O)(C2=CC=C(Cl)C([N+]([O-])=O)=C2)=O

-20°C, 3 years; 4°C, 2 years (Powder)

12352200