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ProductsBack/CTPI-2 [68003-38-3]

CTPI-2 [68003-38-3]

Research Use Only
HY-123986
MedChem Express
CAS Number68003-38-3
DownloadMSDS
Product group Chemicals
Estimated Purity99.95
Molecular Weight356.74
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CTPI-2 [68003-38-3]
  • Delivery Days Customer
    10
  • CAS Number
    68003-38-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.95
  • Molecular Formula
    C13H9ClN2O6S
  • Molecular Weight
    356.74
  • Scientific Description
    CTPI-2 is a third-generation mitochondrial citrate carrier SLC25A1 inhibitor with a KD of 3.5 microM. CTPI-2 inhibits glycolysis, PPARgamma, and its downstream target the glucose transporter GLUT4. CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet. Antitumor activity[1][2].
  • SMILES
    O=C(O)C1=CC=CC=C1NS(=O)(C2=CC=C(Cl)C([N+]([O-])=O)=C2)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200