Cathepsin B Polyclonal Antibody

Elabscience

Cathepsin B Polyclonal Antibody

12

ImmunoHistoChemistry

ELISA IHC

Research Use Only

Polyclonal

0.8 mg/ml

Unconjugated

CTSB

cathepsin B

APPS, CPSB, KWE, RECEUP, cathepsin B, APP secretase, amyloid precursor protein secretase, cathepsin B1, cysteine protease, epididymis secretory sperm binding protein, keratolytic winter erythema (Oudtshoorn skin disease)

Rabbit

IgG

Cathepsin B

The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.

-20°C

41116161