Cullin 4b antibody
GTX113875
Overview
- SupplierGeneTex
- Product NameCullin 4b antibody
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.33 mg/ml
- ConjugateUnconjugated
- Gene ID8450
- Target nameCUL4B
- Target descriptioncullin 4B
- Target synonymsCUL-4B; cullin-4B; MRXHF2; MRXS15; MRXSC; SFM2
- HostRabbit
- IsotypeIgG
- Protein IDQ13620
- Protein NameCullin-4B
- Scientific DescriptionThis gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Ubiquitin hydrolase UCH-L1 destabilizes mTOR complex 1 by antagonizing DDB1-CUL4-mediated ubiquitination of raptor. Hussain S et al., 2013 Mar, Mol Cell BiolRead more
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