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Cullin 4b antibody

GTX129298
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCUL4B
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cullin 4b antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.75 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8450
  • Target name
    CUL4B
  • Target description
    cullin 4B
  • Target synonyms
    CUL-4B; cullin-4B; MRXHF2; MRXS15; MRXSC; SFM2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13620
  • Protein Name
    Cullin-4B
  • Scientific Description
    This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Human DNA Ligase I Interacts with and Is Targeted for Degradation by the DCAF7 Specificity Factor of the Cul4-DDB1 Ubiquitin Ligase Complex. Peng Z et al., 2016 Oct 14, J Biol Chem
    Read more

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