Curcumin

Selleck Chemicals

Curcumin [458-37-7]

9

458-37-7

Research Use Only

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Curcumin (Diferuloylmethane, Natural Yellow 3, Turmeric yellow) is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase (IC50~25 microM) and Histone deacetylase (HDAC); activates Nrf2 pathway and supresses the activation of NF-kappaB. Curcumin induces mitophagy, autophagy, apoptosis, and cell cycle arrest with antitumor activity. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus, hepatitis C virus, HIV and so on.

-80°C

51202000