CXCL11 antibody

GeneTex

CXCL11 antibody

9

WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

Unconjugated

CXCL11

C-X-C motif chemokine ligand 11

H174, I-TAC, IP-9, IP9, SCYB11, SCYB9B, b-R1, C-X-C motif chemokine 11, beta-R1, chemokine (C-X-C motif) ligand 11, interferon gamma-inducible protein 9, interferon-inducible T-cell alpha chemoattractant, small inducible cytokine B11, small inducible cytokine subfamily B (Cys-X-Cys), member 11, small inducible cytokine subfamily B (Cys-X-Cys), member 9B

Chicken

IgY

C-X-C motif chemokine 11

Chemotactic for interleukin-activated T-cells but not unstimulated T-cells. neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. Chemokines are a group of small (approximately 8 to 14 kD). mostly basic. structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane. G protein-coupled receptors. Chemokines also play fundamental roles in the development. homeostasis. and function of the immune system. and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies. CXC and CC. This protein is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene.

Human

-20°C or -80°C,2°C to 8°C

12352203