CXCL8 / IL8 antibody [I8-60]

GeneTex

CXCL8 / IL8 antibody [I8-60]

9

This antibody recognises both recombinant and native IL8. It does not cross react with Monocyte Chemotactic Activating Factor (MCAF)or Regulated on Activation, Normal T-cell Expressed, and Secreted (RANTES).

For ELISA: Use at an assay dependent dilution. Can be used as a detection antibody in an ELISA pair with GTX18649 (capture). For Neut: Use at a concentration of 5 microg/ml with 10 ng/ml IL8 for 98.4% inhibition of chemotactic activity. For WB: Use at a concentration of 0.02 - 0.1 microg/ml. Predicted molecular weight: 11 kDa. Optimal dilutions/concentrations should be determined by the end user.

Western Blot, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

I8-60

1 mg/ml

Unconjugated

Liquid

CXCL8

C-X-C motif chemokine ligand 8

alveolar macrophage chemotactic factor I; beta endothelial cell-derived neutrophil activating peptide; beta-thromboglobulin-like protein; chemokine (C-X-C motif) ligand 8; emoctakin; GCP1; GCP-1; granulocyte chemotactic protein 1; IL8; interleukin 8; interleukin-8; LECT; LUCT; lung giant cell carcinoma-derived chemotactic protein; lymphocyte derived neutrophil activating peptide; LYNAP; MDNCF; MONAP; monocyte-derived neutrophil chemotactic factor; monocyte-derived neutrophil-activating peptide; NAF; NAP1; NAP-1; neutrophil-activating peptide 1; SCYB8; small inducible cytokine subfamily B, member 8; T-cell chemotactic factor; tumor necrosis factor-induced gene 1

Mouse

IgG1

Interleukin-8

The protein encoded by this gene is a member of the CXC chemokine family and is a major mediator of the inflammatory response. The encoded protein is secreted primarily by neutrophils, where it serves as a chemotactic factor by guiding the neutrophils to the site of infection. This chemokine is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other members of the CXC chemokine gene family form a gene cluster in a region of chromosome 4q. [provided by RefSeq, Aug 2017]

Human

-20°C or -80°C,2°C to 8°C

12352203