ICC/IF analysis of HeLa cells using GTX22074 CXCR4 antibody. Working concentration : 2 μg/ml
ICC/IF analysis of HeLa cells using GTX22074 CXCR4 antibody. Working concentration : 2 μg/ml
CXCR4 antibody
GTX22074
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCXCR4
Overview
- SupplierGeneTex
- Product NameCXCR4 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1-2 microg/mL. ICC/IF: 2-20 microg/mL. IHC-P: 5 microg/mL. FACS: 0.1 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID7852
- Target nameCXCR4
- Target descriptionC-X-C motif chemokine receptor 4
- Target synonymsCD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS, WHIMS1, C-X-C chemokine receptor type 4, CD184 antigen, LPS-associated protein 3, SDF-1 receptor, chemokine (C-X-C motif) receptor 4, fusin, leukocyte-derived seven transmembrane domain receptor, lipopolysaccharide-associated protein 3, neuropeptide Y receptor Y3, neuropeptide Y3 receptor, seven transmembrane helix receptor, seven-transmembrane-segment receptor, spleen, stromal cell-derived factor 1 receptor
- HostRabbit
- IsotypeIgG
- Protein IDP61073
- Protein NameC-X-C chemokine receptor type 4
- Scientific DescriptionThis gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chang TM, Chiang YC, Lee CW, et al. CXCL14 promotes metastasis of non-small cell lung cancer through ACKR2-depended signaling pathway. Int J Biol Sci. 2023,19(5):1455-1470. doi: 10.7150/ijbs.79438Read this paper
- Kamada S, Ikeda K, Suzuki T, et al. Clinicopathological and Preclinical Patient-Derived Model Studies Define High Expression of NRN1 as a Diagnostic and Therapeutic Target for Clear Cell Renal Cell Carcinoma. Front Oncol. 2021,11:758503. doi: 10.3389/fonc.2021.758503Read this paper
- Leng M, Peng Y, Pan M, et al. Experimental Study on the Effect of Allogeneic Endothelial Progenitor Cells on Wound Healing in Diabetic Mice. J Diabetes Res. 2021,2021:9962877. doi: 10.1155/2021/9962877Read this paper
- Kun-Ming C, Chih-Hsien C, Chen-Fang L, et al. Potential Anticancer Effect of Celastrol on Hepatocellular Carcinoma by Suppressing CXCR4-related Signal and Impeding Tumor Growth in Vivo. Arch Med Res. 2020,51(4):297-302. doi: 10.1016/j.arcmed.2020.03.001Read this paper
- Feng H, Liu Y, Bian X, et al. ALDH1A3 affects colon cancer in vitro proliferation and invasion depending on CXCR4 status. Br J Cancer. 2018,118(2):224-232. doi: 10.1038/bjc.2017.363Read this paper
- Zhao Z, Bauer N, Aleksandrowicz E, et al. Intraductal papillary mucinous neoplasm of the pancreas rapidly xenografts in chicken eggs and predicts aggressiveness. Int J Cancer. 2018,142(7):1440-1452. doi: 10.1002/ijc.31160Read this paper
- Zhang Y, Liu L, Fan P, et al. Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer. Oncotarget. 2015,6(12):9999-10015.Read this paper
- Isayev O, Rausch V, Bauer N, et al. Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine. Oncotarget. 2014,5(13):5177-89.Read this paper
- Jin UH, Lee SO, Pfent C, et al. The aryl hydrocarbon receptor ligand omeprazole inhibits breast cancer cell invasion and metastasis. BMC Cancer. 2014,14:498. doi: 10.1186/1471-2407-14-498Read this paper
Datasheet
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![Non-transfected (–) and transfected (+) boiled and unboiled 293T whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with CXCR4 antibody [HL2612] (GTX639064) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX639064/GTX639064_T-45166_20230929_WB_B_23100319_579.webp)
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ReactivityCanine, Human, Mouse
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