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FACS analysis of HeLa cells using GTX22074 CXCR4 antibody. Working concentration : 0.1 microg/ml Purple: cells without staining Green: Isotype control Red : CXCR4 antibody
FACS analysis of HeLa cells using GTX22074 CXCR4 antibody. Working concentration : 0.1 microg/ml Purple: cells without staining Green: Isotype control Red : CXCR4 antibody
FACS analysis of HeLa cells using GTX22074 CXCR4 antibody. Working concentration : 0.1 microg/ml Purple: cells without staining Green: Isotype control Red : CXCR4 antibody

CXCR4 antibody

GTX22074
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
DownloadDatasheet
Product group Antibodies
TargetCXCR4
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Overview

  • Supplier
    GeneTex
  • Product Name
    CXCR4 antibody - KO/KD Validated
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1-2 microg/mL. ICC/IF: 2-20 microg/mL. IHC-P: 5 microg/mL. FACS: 0.1 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7852
  • Target name
    CXCR4
  • Target description
    C-X-C motif chemokine receptor 4
  • Target synonyms
    CD184; CD184 antigen; chemokine (C-X-C motif) receptor 4; C-X-C chemokine receptor type 4; D2S201E; FB22; fusin; HM89; HSY3RR; LAP3; LAP-3; LCR1; LESTR; leukocyte-derived seven transmembrane domain receptor; lipopolysaccharide-associated protein 3; LPS-associated protein 3; neuropeptide Y receptor Y3; neuropeptide Y3 receptor; NPY3R; NPYR; NPYRL; NPYY3R; SDF-1 receptor; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor; WHIM; WHIMS; WHIMS1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP61073
  • Protein Name
    C-X-C chemokine receptor type 4
  • Scientific Description
    This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • CXCL14 promotes metastasis of non-small cell lung cancer through ACKR2-depended signaling pathway.
    Read more
  • Clinicopathological and Preclinical Patient-Derived Model Studies Define High Expression of NRN1 as a Diagnostic and Therapeutic Target for Clear Cell Renal Cell Carcinoma. Kamada S et al., 2021, Front Oncol
    Read more
  • Experimental Study on the Effect of Allogeneic Endothelial Progenitor Cells on Wound Healing in Diabetic Mice. Leng M et al., 2021, J Diabetes Res
    Read more
  • Potential Anticancer Effect of Celastrol on Hepatocellular Carcinoma by Suppressing CXCR4-related Signal and Impeding Tumor Growth in Vivo. Kun-Ming C et al., 2020 May, Arch Med Res
    Read more
  • ALDH1A3 affects colon cancer in vitro proliferation and invasion depending on CXCR4 status. Feng H et al., 2018 Jan, Br J Cancer
    Read more
  • Intraductal papillary mucinous neoplasm of the pancreas rapidly xenografts in chicken eggs and predicts aggressiveness. Zhao Z et al., 2018 Apr 1, Int J Cancer
    Read more
  • Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer. Zhang Y et al., 2015 Apr 30, Oncotarget
    Read more
  • Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine. Isayev O et al., 2014 Jul 15, Oncotarget
    Read more
  • The aryl hydrocarbon receptor ligand omeprazole inhibits breast cancer cell invasion and metastasis. Jin UH et al., 2014 Jul 9, BMC Cancer
    Read more

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