
WB analysis of mouse lung tissue lysate (35ug/lane) using GTX81231 CYP1A1 antibody, Internal.
CYP1A1 antibody, Internal
GTX81231
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetCYP1A1
Overview
- SupplierGeneTex
- Product NameCYP1A1 antibody, Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. ICC/IF: 1:10-1:50. IHC-P: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1543
- Target nameCYP1A1
- Target descriptioncytochrome P450 family 1 subfamily A member 1
- Target synonymsAHH; AHRR; aryl hydrocarbon hydroxylase; CP11; CYP1; CYPIA1; cytochrome P1-450, dioxin-inducible; cytochrome P450 1A1; cytochrome P450 form 6; cytochrome P450, family 1, subfamily A, polypeptide 1; cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1; cytochrome P450-C; cytochrome P450-P1; flavoprotein-linked monooxygenase; hydroperoxy icosatetraenoate dehydratase; P1-450; P450-C; P450DX; xenobiotic monooxygenase
- HostRabbit
- IsotypeIgG
- Protein IDP04798
- Protein NameCytochrome P450 1A1
- Scientific DescriptionThis gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzymes endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203