Western blot analysis of extracts from HuvEc cells, using Cytochrome P450 2C8 antiobdy.
Western blot analysis of extracts from HuvEc cells, using Cytochrome P450 2C8 antiobdy.
CYP2C8 Antibody
CSB-PA694882
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCYP2C8
Overview
- SupplierCusabio
- Product NameCYP2C8 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1558
- Target nameCYP2C8
- Target descriptioncytochrome P450 family 2 subfamily C member 8
- Target synonymsCPC8; CYP2C8DM; CYPIIC8; cytochrome P450 2C8; cytochrome P450 form 1; cytochrome P450 IIC2; cytochrome P450 MP-12; cytochrome P450 MP-20; cytochrome P450, family 2, subfamily C, polypeptide 8; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8; flavoprotein-linked monooxygenase; microsomal monooxygenase; MP-12/MP-20; P450 form 1; s-mephenytoin 4-hydroxylase; xenobiotic monooxygenase
- HostRabbit
- IsotypeIgG
- Protein IDP10632
- Protein NameCytochrome P450 2C8
- Scientific DescriptionCytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol). Romkes M., Biochemistry 30:3247-3255(1991). Ged C., Biochim. Biophys. Acta 1088:433-435(1991). Zeldin D.C., Arch. Biochem. Biophys. 322:76-86(1995).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203