Bio-Connect

CYP3cide [1390637-82-7]

HY-18642
MedChem Express
CAS Number1390637-82-7
Product group Chemicals
Estimated Purity99.92
Molecular Weight456.59
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CYP3cide [1390637-82-7]
  • Delivery Days Customer
    10
  • CAS Number
    1390637-82-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.92
  • Molecular Formula
    C26H32N8
  • Molecular Weight
    456.59
  • Scientific Description
    CYP3cide (PF-4981517) is a potent, selective and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4). The IC50 values for Midazolam 1-hydroxylase activity are 0.03 microM, 17 microM, and 71 microM for CYP3A4, CYP3A5, and CYP3A7, respectively. CYP3cide can be used to distinguish the contributions of CYP3A4 versus CYP3A5 on agent metabolism[1].
  • SMILES
    CC1=CC=C(C2=C(C3=NN(C)C4=NC=NC(N5C[C@@H](N6CCCCC6)CC5)=C43)C=NN2C)C=C1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200