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Cytochrome C antibody

GTX108585
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCYCS
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cytochrome C antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.18 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID54205
  • Target name
    CYCS
  • Target description
    cytochrome c, somatic
  • Target synonyms
    CYC, HCS, THC4, cytochrome c
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP99999
  • Protein Name
    Cytochrome c
  • Scientific Description
    This gene encodes cytochrome c, a component of the electron transport chain in mitochondria. The heme group of cytochrome c accepts electrons from the b-c1 complex and transfers electrons to the cytochrome oxidase complex. Cytochrome c is also involved in initiation of apoptosis. Upon release of cytochrome c to the cytoplasm, the protein binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Many cytochrome c pseudogenes exist, scattered throughout the human genome. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • García-Arroyo R, Marfany G, Mirra S. CERKL, a Retinal Dystrophy Gene, Regulates Mitochondrial Transport and Dynamics in Hippocampal Neurons. Int J Mol Sci. 2022,23(19). doi: 10.3390/ijms231911593
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  • Lee CW, Huang CC, Chi MC, et al. Naringenin Induces ROS-Mediated ER Stress, Autophagy, and Apoptosis in Human Osteosarcoma Cell Lines. Molecules. 2022,27(2). doi: 10.3390/molecules27020373
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  • Huang FL, Yu SJ, Liao EC, et al. Niclosamide suppresses T‑cell acute lymphoblastic leukemia growth through activation of apoptosis and autophagy. Oncol Rep. 2022,47(2):pii: 30. doi: 10.3892/or.2021.8241.
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  • Hu H, Deng X, Song Q, et al. Mitochondria-targeted accumulation of oxygen-irrelevant free radicals for enhanced synergistic low-temperature photothermal and thermodynamic therapy. J Nanobiotechnology. 2021,19(1):390. doi: 10.1186/s12951-021-01142-6
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  • Clough E, Inigo J, Chandra D, et al. Mitochondrial Dynamics in SARS-COV2 Spike Protein Treated Human Microglia: Implications for Neuro-COVID. J Neuroimmune Pharmacol. 2021,16(4):770-784. doi: 10.1007/s11481-021-10015-6
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  • Yang DQ, Zuo QN, Wang T, et al. Mitochondrial-Targeting Antioxidant SS-31 Suppresses Airway Inflammation and Oxidative Stress Induced by Cigarette Smoke. Oxid Med Cell Longev. 2021,2021:6644238. doi: 10.1155/2021/6644238
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  • Liao MF, Yeh SR, Lu KT, et al. Interactions between Autophagy, Proinflammatory Cytokines, and Apoptosis in Neuropathic Pain: Granulocyte Colony Stimulating Factor as a Multipotent Therapy in Rats with Chronic Constriction Injury. Biomedicines. 2021,9(5). doi: 10.3390/biomedicines9050542
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  • Cornelissen T, Spinazzi M, Martin S, et al. CHCHD2 harboring Parkinson's disease-linked T61I mutation precipitates inside mitochondria and induces precipitation of wild-type CHCHD2. Hum Mol Genet. 2020,29(7):1096-1106. doi: 10.1093/hmg/ddaa028
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