Cytokeratin 16 antibody [LL025]

GeneTex

Cytokeratin 16 antibody [LL025]

9

IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

LL025

Unconjugated

KRT16

keratin 16

CK16; cytokeratin 16; FNEPPK; focal non-epidermolytic palmoplantar keratoderma; K16; K1CP; keratin 16, type I; keratin, type I cytoskeletal 16; KRT16A; NEPPK; PC1

Mouse

IgG1

Keratin, type I cytoskeletal 16

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus. [provided by RefSeq, Jul 2008]

Human

2°C to 8°C

12352203