![D-I03 [688342-78-1] D-I03 [688342-78-1]](https://www.targetmol.com/group3/M00/36/0B/CgoaEGayNQOEBGjbAAAAADjEXlg648.png)
D-I03 [688342-78-1]
T10936
CAS Number688342-78-1
Product group Chemicals
Estimated Purity99.04%
Molecular Weight428.64
Overview
- SupplierTargetMol Chemicals
- Product NameD-I03 [688342-78-1]
- Delivery Days Customer9
- CAS Number688342-78-1
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameD-I03
- Estimated Purity99.04%
- Molecular FormulaC23H36N6S
- Molecular Weight428.64
- Scientific DescriptionD-I03 is a selective RAD52 inhibitor with a Kd of 25.8 microM. It specifically inhibits RAD52-dependent single-chain annealing (SSA) and D-loop formation, with IC50 values of 5 microM and 8 microM, respectively. D-I03 also inhibits the growth of BRCA1 and BRCA2 deficient cells and prevents the formation of damage-induced RAD52 foci, but does not affect RAD51 foci induced by Cisplatin.
- Shelf life instruction3 years
- SMILESCCN(CC)CCNC(=S)Nc1ccc2nc(cc(C)c2c1)N1CCN(CC)CC1
- Storage Instruction-20°C
- UNSPSC12352200