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D-I03 [688342-78-1]

D-I03 [688342-78-1]

T10936
TargetMol Chemicals
CAS Number688342-78-1
Product group Chemicals
Estimated Purity99.04%
Molecular Weight428.64
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    D-I03 [688342-78-1]
  • Delivery Days Customer
    9
  • CAS Number
    688342-78-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    D-I03
  • Estimated Purity
    99.04%
  • Molecular Formula
    C23H36N6S
  • Molecular Weight
    428.64
  • Scientific Description
    D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 microM. It specifically inhibits RAD52-dependent single-chain annealing (SSA) and D-loop formation, with IC50 values of 5 microM and 8 microM, respectively. D-I03 also inhibits the growth of BRCA1 and BRCA2 deficient cells and prevents the formation of damage-induced RAD52 foci, but does not affect RAD51 foci induced by Cisplatin.
  • Shelf life instruction
    3 years
  • SMILES
    CCN(CC)CCNC(=S)Nc1ccc2nc(cc(C)c2c1)N1CCN(CC)CC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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