D-I03 [688342-78-1]

TargetMol Chemicals

D-I03 [688342-78-1]

9

688342-78-1

Chemical

Research Use Only

D-I03

99.04%

C23H36N6S

428.64

D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 microM. It specifically inhibits RAD52-dependent single-chain annealing (SSA) and D-loop formation, with IC50 values of 5 microM and 8 microM, respectively. D-I03 also inhibits the growth of BRCA1 and BRCA2 deficient cells and prevents the formation of damage-induced RAD52 foci, but does not affect RAD51 foci induced by Cisplatin.

3 years

CCN(CC)CCNC(=S)Nc1ccc2nc(cc(C)c2c1)N1CCN(CC)CC1

-20°C

12352200