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Western Blot analysis of Hela cell using DAB2 Polyclonal Antibody at dilution of 1:350
Western Blot analysis of Hela cell using DAB2 Polyclonal Antibody at dilution of 1:350
Western Blot analysis of Hela cell using DAB2 Polyclonal Antibody at dilution of 1:350

DAB2 Polyclonal Antibody

Research Use Only
E-AB-14925
Elabscience
Product group Antibodies
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    Elabscience
  • Product Name
    DAB2 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA WB IHC
  • Certification
    Research Use Only
  • Concentration
    0.6mg/ml
  • Scientific Description
    This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • UNSPSC
    12352203