DAND5 antibody [25D4]

GeneTex

DAND5 antibody [25D4]

9

ELISA: 1:1000 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ELISA

Research Use Only

Monoclonal

25D4

Unconjugated

DAND5

DAN domain BMP antagonist family member 5

CER2; cerberus 2; cerberus-like 2; cerberus-like protein 2; CERL2; cerl-2; CKTSF1B3; COCO; CRL2; cysteine knot superfamily 1, BMP antagonist 3; DAN domain family member 5; DAN domain family member 5, BMP antagonist; DAN domain family, member 5; DANTE; GREM3; gremlin-3; SP1

Mouse

IgG1

DAN domain family member 5

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203