DAP3 antibody, C-term

GeneTex

DAP3 antibody, C-term

7

This antibody is expected to recognise isoform 1 (NP_387506.1), isoform 2 (NP_001186779.1) and isoform 3 (NP_001186780.1).

WB: 1-3microg/ml. ICC/IF: 5microg/ml. IHC-P: 2.5microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

DAP3

death associated protein 3

28S ribosomal protein S29, mitochondrial; bMRP-10; DAP-3; ionizing radiation resistance conferring protein; mitochondrial 28S ribosomal protein S29; mitochondrial small ribosomal subunit protein mS29; MRPS29; MRP-S29; S29mt

Goat

IgG

28S ribosomal protein S29, mitochondrial

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Dec 2010]

Human

-20°C or -80°C,2°C to 8°C

12352203