Dasatinib (GMP)
HY-10181G
CAS Number302962-49-8
Product group Chemicals
Molecular Weight488.01
Overview
- SupplierMedChem Express
- Product NameDasatinib (GMP)
- Delivery Days Customer5
- CAS Number302962-49-8
- CertificationResearch Use Only
- Molecular FormulaC22H26ClN7O2S
- Molecular Weight488.01
- Scientific DescriptionDasatinib (BMS-354825) (GMP) is a GMP-grade Dasatinib (HY-10181). GMP-grade small molecules can be used as adjuvant agents in cell therapy. Dasatinib (BMS-354825) is an orally active, ATP-competitive, dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Ki values for Src and Bcr-Abl are 16 pM and 30 pM, respectively. Dasatinib inhibits Bcr-Abl and Src with IC50 values of less than 1.0 nM and 0.5 nM, respectively. Dasatinib also induces apoptosis and autophagy[1].
- SMILESO=C(C1=CN=C(S1)NC2=NC(C)=NC(N3CCN(CC3)CCO)=C2)NC4=C(C=CC=C4Cl)C
- UNSPSC12352200
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