Dasatinib (hydrochloride)
HY-10181A
CAS Number854001-07-3
Product group Chemicals
Estimated Purity99.67
Molecular Weight524.47
Overview
- SupplierMedChem Express
- Product NameDasatinib (hydrochloride)
- Delivery Days Customer4
- CAS Number854001-07-3
- CertificationResearch Use Only
- Estimated Purity99.67
- Molecular FormulaC22H27Cl2N7O2S
- Molecular Weight524.47
- Scientific DescriptionDasatinib (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib hydrochloride inhibits Bcr-Abl and Src with IC50s of [1]. Dasatinib hydrochloride also induces apoptosis and autophagy.
- SMILESO=C(C1=CN=C(S1)NC2=NC(C)=NC(N3CCN(CC3)CCO)=C2)NC4=C(C=CC=C4Cl)C.[H]Cl
- Storage Instruction4°C (Powder, stored under nitrogen)
- UNSPSC12352200
![Dasatinib hydrochloride [854001-07-3]](https://www.targetmol.com/group3/M00/36/D2/CgoaEGayRBSEHobPAAAAANht3y4052.png)