Dasatinib hydrochloride [854001-07-3]
T22303
CAS Number854001-07-3
Product group Chemicals
Estimated Purity99.98%
Molecular Weight524.47
Overview
- SupplierTargetMol Chemicals
- Product NameDasatinib hydrochloride [854001-07-3]
- Delivery Days Customer4
- CAS Number854001-07-3
- CertificationResearch Use Only
- Chemical NameDasatinib hydrochloride
- Estimated Purity99.98%
- Molecular FormulaC22H27Cl2N7O2S
- Molecular Weight524.47
- Scientific DescriptionDasatinib hydrochloride (BMS-354825 HCl) (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib hydrochloride hydrochloride inhibits Bcr-Abl and Src with IC50s of <1.0 nM and 0.5 nM, respectively. Dasatinib hydrochloride hydrochloride also induces Apoptosis and Autophagy.
- Shelf life instruction3 years
- SMILESCl.Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1
- Storage Instruction-20°C
- UNSPSC12352200
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