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DCPIB

E0001
Selleck Chemicals
Estimated Purity...
Product group Chemicals
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    DCPIB [82749-70-0]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Estimated Purity
    ...
  • Scientific Description
    DCPIB is a specific and potent inhibitor of volume-regulated anion channels (VRAC). DCPIB potently inhibits several K2P channels with no voltage dependence, including TRESK, TASK1, and TASK3. DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 microM, demonstrating at least 100-fold higher affinity over TREK1/TRAAK channels. DCPIB is also a novel selective blocker of I(Cl,swell), which blocks native I(Cl,swell) of calf bovine pulmonary artery endothelial (CPAE) cells with an IC(50) of 4.1 microM.
  • UNSPSC
    51202000

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