More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/DDB2 Antibody
Western Blot Positive WB detected in: Mouse liver tissue, Rat liver tissue All lanes: DDB2 antibody at 4.9ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 48, 27, 18, 41 kDa Observed band size: 48 kDa
Western Blot Positive WB detected in: Mouse liver tissue, Rat liver tissue All lanes: DDB2 antibody at 4.9ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 48, 27, 18, 41 kDa Observed band size: 48 kDa
Western Blot Positive WB detected in: Mouse liver tissue, Rat liver tissue All lanes: DDB2 antibody at 4.9ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 48, 27, 18, 41 kDa Observed band size: 48 kDa

DDB2 Antibody

CSB-PA846067LA01HU
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetDDB2
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    Cusabio
  • Product Name
    DDB2 Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID1643
  • Target name
    DDB2
  • Target description
    damage specific DNA binding protein 2
  • Target synonyms
    damage-specific DNA binding protein 2, 48kDa; DDB p48 subunit; DDBB; DNA damage-binding protein 2; UV-damaged DNA-binding protein 2; UV-DDB 2; UV-DDB2; xeroderma pigmentosum group E protein; XPE
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ92466
  • Protein Name
    DNA damage-binding protein 2
  • Scientific Description
    Required for DNA repair. Binds to DDB1 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches. Also appears to function as the substrate recognition module for the DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex DDB1-CUL4-ROC1 (also known as CUL4-DDB-ROC1 and CUL4-DDB-RBX1). The DDB1-CUL4-ROC1 complex may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage. The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair. The DDB1-CUL4-ROC1 complex also ubiquitinates XPC, which may enhance DNA-binding by XPC and promote NER. Isoform D1 and isoform D2 inhibit UV-damaged DNA repair.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

Related products

Product group Antibodies
RayBiotech
Anti-DDB2 Antibody144-01848
ApplicationsImmunoFluorescence, Western Blot
TargetDDB2
  • SizePrice
Formalin-fixed and paraffin embedded rat intestine labeled with Anti-DDB2 Polyclonal Antibody, Unconjugated (bs-2599R) at 1:300 followed by conjugation to the secondary antibody and DAB staining.
Product group Antibodies
Bioss Antibodies
DDB2 Polyclonal AntibodyBS-2599R
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
TargetDDB2
  • SizePrice
Product group Antibodies
Biomatik
Ddb2 Polyclonal AntibodyCAC11261
ApplicationsWestern Blot, ELISA
TargetDDB2
  • SizePrice
Product group Antibodies
Assay Genie
MIER1 AntibodyCAB18480
TargetDDB2
  • SizePrice
Product group Antibodies
LifeSpan BioSciences
DDB2 AntibodyLS-C331725
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry
TargetDDB2
  • SizePrice
Immunohistochemistry analysis in human esophagus and skeletal muscle tissues using HPA058406 antibody. Corresponding DDB2 RNA-seq data are presented for the same tissues.
Product group Antibodies
Atlas Antibodies
Anti-DDB2 AntibodyHPA058406
ApplicationsImmunoCytoChemistry, ImmunoHistoChemistry
ReactivityHuman
TargetDDB2
  • SizePrice
Figure 1. Western blot analysis of DDB2 using anti-DDB2 antibody (A01430-2). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 ug of sample under reducing conditions. Lane 1: human Hela whole cell lysates, Lane 2: human A431 whole cell lysates, Lane 3: human Raji whole cell lysates, Lane 4: human HL-60 whole cell lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat milk/TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-DDB2 antigen affinity purified polyclonal antibody (Catalog # A01430-2) at 0.5 microg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:5000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for DDB2 at approximately 48 kDa. The expected band size for DDB2 is at 48 kDa.
Product group Antibodies
Boster Bio
Anti-DDB2 Antibody Picoband(r)A01430-2-CARRIER-FREE
ApplicationsFlow Cytometry, Western Blot, ELISA
TargetDDB2
  • SizePrice
WB analysis of various sample lysates using GTX54039 DDB2 antibody. Dilution : 1:500 Loading : 25microg per lane
Product group Antibodies
GeneTex
DDB2 antibodyGTX54039
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
TargetDDB2
  • SizePrice
Anti-DDB2 Antibody
Product group Antibodies
Antibodies.com
Anti-DDB2 AntibodyA29839
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry
  • SizePrice
Product group Antibodies
MedChem Express
DDB2 Antibody (YA2127, Rabbit)HY-P82382
TargetDDB2
  • SizePrice