Decitabine

MedChem Express

Decitabine [2353-33-5]

10

2353-33-5

Research Use Only

99.97

C8H12N4O4

228.21

Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis . Decitabine has potent anticancer activity [1] [2] .

O[C@H]1C[C@H](N2C(N=C(N)N=C2)=O)O[C@@H]1CO

2°C to 8°C

12352200