Dectin-1/CLEC7A Protein, Mouse (HEK293)

MedChem Express

Dectin-1/CLEC7A Protein, Mouse (HEK293)

14

Research Use Only

95.0

Clec7a

C-type lectin domain family 7, member a

beta-; beta-glucan receptor; beta-GR; BG; BGR; Clecsf; Clecsf12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; dectin; dectin-1; dendritic cell-associated C-type lectin 1

C-type lectin domain family 7 member A

Dectin-1/CLEC7A acts as a lectin and specifically recognizes beta-1,3-linked and beta-1,6-linked glucans in bacterial and fungal cell walls. Dectin-1/CLEC7A is critical for Toll-like receptor 2 (TLR2)-mediated inflammation by recruiting SYK through its immunoreceptor tyrosine-based activation motif (ITAM), thereby activating NF-kappa-B. Dectin-1/CLEC7A Protein, Mouse (HEK293, N-His) is the recombinant mouse-derived Dectin-1/CLEC7A protein, expressed by HEK293 , with N-His labeled tag.

-20°C

41116100