Degrasyn [856243-80-6]

MedChem Express

Degrasyn [856243-80-6]

10

856243-80-6

Research Use Only

99.70

C19H18BrN3O

384.27

Degrasyn (WP1130) is a cell-permeable deubiquitinase (DUB) inhibitor, directly inhibiting DUB activity of USP9x, USP5, USP14, and UCH37. Degrasyn has been shown to downregulate the antiapoptotic proteins Bcr-Abl and JAK2.

BrC1=CC=CC(/C=C(C(N[C@H](C2=CC=CC=C2)CCC)=O)\C#N)=N1

-20°C,2°C to 8°C

12352200